Vitamin D As A Predictor of Severity in Patients With Cirrhosis of Liver

Abstract

Background: In patients with chronic liver diseases, the prevalence of vitamin D deficits is much higher and practically universal. Vitamin D deficiency has been associated with increased mortality, bacterial infections, portal hypertension complications and fibrosis severity. The study was done to assess the relation of vitamin D deficiency to the severity in patients with liver cirrhosis as evidenced by CTP and MELD score. Methods: Study included 50 patients with chronic liver disease of various etiologies, vitamin D levels measured in all patients. Results: Vitamin D deficiency observed in 50 patients, insufficiency (10–30) in 31 patients, deficiency (<10) in 19 patients. 2 patients with CTP Class A had insufficiency, 10 patients with CTP Class B had insufficiency, 19 patients in CTP C had severe deficiency. 13 patients with MELD <15 has insufficiency, 18 and 13 with MELD 15–24 had insufficiency and deficiency respectively, 6 patients with MELD >25 had deficiency. Conclusion: This study was conducted to study the relation of vitamin D deficiency to the severity in patients with liver cirrhosis as evidenced by CTP and MELD score. Vitamin D deficiency was severe in cirrhotic patients in Child–Pugh class C and MELD score >25. The authors have none to declare.