Abstract
What are the recommended intakes for vitamin D? What concentration of 25-hydoxyvitamin D delineates “normal” from vitamin D deficient? These recurring questions have received considerable attention and debate. The Institute of Medicine (IOM) used a systematic, evidence-based review approach to make its recommended dietary allowances for vitamin D, including a critical evaluation of the plethora of evidence relevant to the role of vitamin D in human health and disease. According to the 2011 IOM report (1), despite a large body of scientific evidence supporting the potential role of vitamin D in preventing cardiovascular disease and type 2 diabetes, these data were deemed insufficient to inform nutritional requirements. How could such substantial evidence have had minimal influence on the IOM recommended intakes for vitamin D? In a recent commentary in …
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