Abstract
Adult, male rats bred for over 10 generations on a soy meal-corn-diet had vitamin B12 values of liver and kidney about 10 times lower than the controls. If the deficient ration was supplemented with 5µg/kg of B12, these values were still about 1/5 of the controls. 3 weeks on the deficient diet lowered the B12 levels in the livers and kidneys of previously undepleted rats to about 1/2, and a similar diet containing 0.1% of iodized casein lowered these levels to about 1/3 of the normal values but did not lower the B12-concentration of organs of already deficient rats. Rats bred on the deficient diet and receiving for 1 month a supplement of 30µg/kg of vitamin B12 or the stock diet with a similar B12-content, had normal B12-levels in livers and kidneys.
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