Abstract
ObjectiveTo determine the prevalence of vitamin B12 deficiency and examine the associations between maternal and infant vitamin B12 and folate status in a cohort of healthy pregnant adolescents.DesignSerum vitamin B12 and folate concentrations were measured in pregnant adolescents at mid‐gestation, delivery, and in cord blood. Linear and binomial regression models were used to examine the associations between maternal and infant vitamin B12 and folate status.ResultsSerum vitamin B12 concentrations decreased significantly during pregnancy (p<0.0001) resulting in an increased prevalence of vitamin B12 deficiency (<148 pmol/L) from mid‐gestation (1.6%) to delivery (15.3%). At delivery, an additional 46.6% of mothers were vitamin B12 insufficient (<200 pmol/L). Maternal vitamin B12 concentrations (p<0.001) and vitamin B12 deficiency (p<0.001) at delivery were associated with infant B12 concentrations, with 1% of infants being vitamin B12 deficient at birth. Similarly, maternal folate concentrations at delivery (p<0.001) were associated with infant folate concentrations.ConclusionsMaternal vitamin B12 and folate status at delivery predicted infant vitamin B12 and folate status in healthy pregnant adolescents.Support or Funding InformationSupported by grants from the United States Department of Agriculture (USDA): USDA 2005‐35200‐15218 and USDA 2010‐34324‐20769; and the Division of Nutritional Sciences, Cornell University
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
