Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid life

David A Denton,Naji Tabet,Rajesh P Abraham,John L Anderson,Anne Ws Rutjes,Muzaffar A Malik,Lee Yee Chong,Aalya S Al-Assaf

doi:10.1002/14651858.cd011904

Abstract

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid life

Highlights

Healthy or successful cognitive ageing can be defined as "not just the absence of cognitive impairment, but the development and preservation of the multi-dimensional cognitive structure that allows the older adult to maintain social connectedness, and ongoing sense of purpose, and the abilities to function independently, to permit functional recovery from illness and injury, and to cope with residual cognitive deficits" but there is no broad consensus on a definition yet (Depp 2012; Hendrie 2006)
Successful cognitive ageing is distinct from mild cognitive impairment (MCI) and dementia
In the early stages of the illness, cognitive deficits are relatively mild, but still a ect the ability to perform some normal daily activities. Those a ected become increasingly dependent on others for all activities of daily living

Summary

Introduction

Description of the conditionCognitive health, mild cognitive impairment and dementiaCognitively healthy or successful cognitive ageing can be defined as "not just the absence of cognitive impairment, but the development and preservation of the multi-dimensional cognitive structure that allows the older adult to maintain social connectedness, and ongoing sense of purpose, and the abilities to function independently, to permit functional recovery from illness and injury, and to cope with residual cognitive deficits" but there is no broad consensus on a definition yet (Depp 2012; Hendrie 2006). Successful cognitive ageing is distinct from mild cognitive impairment (MCI) and dementia. Dementia is a syndrome of cognitive and functional decline that is usually progressive. Most commonly associated with forgetfulness, memory is not the only function that is a ected. In the early stages of the illness, cognitive deficits are relatively mild, but still a ect the ability to perform some normal daily activities. Those a ected become increasingly dependent on others for all activities of daily living. Prior to the onset of the disease, there is usually a stage of mild cognitive impairment (MCI) when cognitive deficits beyond those of normal ageing are detectable, but ordinary activities are not significantly a ected

Objectives

Findings

Methods