Abstract

We present a case of a vitamin A deficient woman who, presented to our clinic with secondary infertility to emphasize the importance of a good history and a multidisciplinary input in the management. This is a rare case of established vitamin A deficiency related to secondary infertility. Secondary infertility was quickly solved (30-45 days) after restoration of Vitamin A levels and the woman managed to get pregnant. It also illustrates that, though highly teratogenic, pregnancies on vita A replacement can be normal. Important fact here is that she was being replaced with vitamin A that her body was deficient in rather than supplementing leading to overdose of vitamin A (as in cases of treatment for Acne etc). Therefore, it may mean that for cases of vitamin A deficient women, termination should not be considered, as replacing normal vitamin A levels does not necessarily lead to hypervitaminosis and therefore increased chances of congenital malformations.

Highlights

  • It has been over 100 years since essential micronutrient vitamin A was firstly described

  • We present a case of a vitamin A deficient woman who, presented to our clinic with secondary infertility to emphasize the importance of a good history and a multidisciplinary input in the management

  • We present a rare case of established vitamin A deficiency related to secondary infertility

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Summary

Introduction

It has been over 100 years since essential micronutrient vitamin A was firstly described. A 28-year old lady, presented in the ophthalmologic department of our hospital, with punctuate staining in the cornea During evaluation of her opthalmological findings, she was found to suffer from Vitamin B12 and Vitamin A deficiency, attributed to gastrointestinal malabsorption. She had been given Vit A supplementation (intramuscular injection of 100000 IU). She attended infertility clinic with, secondary infertility para 2+0 (two vaginal deliveries, 2006 and 2008), of a duration of 48 months. Her menstrual periods were regular and mid luteal progesterone suggested ovulation.

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