Abstract
Upon finishing the sequencing of the first complete human genome in 2004[1],the demand for fast DNA reading with less than$1,000 has been fueled by the ever-increasing awareness for personalized medicine and clinical diagnosis[2,3].Plenty of sequencing techniques,from the original Sanger sequencing method to novel sequencing-by-synthesis technologies(Roche,Solexa,SOLi D,etc.)[3],have been developed rapidly in past decades,which are sug-
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