Abstract
Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging. As a non-destructive biological tissue imaging technology, photoacoustic imaging has important application value in the field of biomedicine. With its high efficiency bioimaging capabilities and excellent biosafety performance, it has been favored by researchers. The visualization of photoacoustic imaging has great research significance in the early diagnosis of some diseases, especially tumors. In photoacoustic imaging, light transmission and thermal effects are important processes. This article is based on COMSOL software and uses finite element analysis to construct a physical model for simulation. Through laser pulses into the stomach tissue containing tumor, the physical process of light transmission and biological heat transfer was studied, and a photothermal model composed of two physical fields was built, and finally a series of visualization graphics were obtained. This work has certain theoretical guiding significance for further promoting the application of photoacoustic imaging in the field of biomedicine.
Highlights
This article is based on COMSOL software and uses finite element analysis to construct a physical model for simulation
Through laser pulses into the stomach tissue containing tumor, the physical process of light transmission and biological heat transfer was studied, and a photothermal model composed of two physical fields was built, and a series of visualization graphics were obtained
Photoacoustic Imaging (PAI) is an emerging non-invasive and non-ionizing biomedical imaging technology based on photoacoustic effect developed in recent years [1] [2] [3] [4] [5]
Summary
Photoacoustic Imaging (PAI) is an emerging non-invasive and non-ionizing biomedical imaging technology based on photoacoustic effect developed in recent years [1] [2] [3] [4] [5]. The medical diagnosis methods for gastric cancer mainly include X-ray, gastroscopy, abdominal ultrasound, CT and positron emission imaging, and tumor markers. These detection methods are mainly for gastric cancer with obvious clinical symptoms, and the ability to diagnose early, especially for small lesions, is weak. The overall process of photoacoustic imaging can be summarized as the tissue absorbs light energy-produces thermal expansion-emits ultrasonic signals, including four physical processes of light transmission, biological heat transfer, solid mechanics and pressure acoustics. The biological heat transfer equation describes the temperature distribution of gray matter and blood vessel
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