Visual indentation apparatus and finite element modelling as a method to characterize 3D mechanical properties of facial skin in vivo

Abstract

Knowledge of the mechanical properties of human skin has essential applications in cosmetic, dermatology and surgical fields. In this study, a hybrid experimental–numerical method was developed to characterize the human skin mechanical properties in vivo. An indentation experiment was physically conducted and simulated by finite element (FE) analysis. In the physical experiment, an indenter made of transparent glass was adopted so that the elliptical eccentricity in the contact area between skin and indenter could be monitored in real-time. In FE simulation, the dermis and subcutaneous tissue were modeled as anisotropic hyperelastic material and isotropic elastic material, respectively. By fitting the FE results to the experimental data, the three-dimensional (3D) mechanical properties of skin, including the dermis and subcutaneous tissue were determined. Furthermore, to demonstrate the ineffectiveness of the hybrid experimental–numerical method, a sensitivity analysis was conducted. In this sensitivity analysis, it is shown that the different mechanical parameters have a different contribution to the final FE result. Finally, the effect of subcutaneous tissue for in vivo skin indentation measurement was also evaluated.