Abstract

To evaluate the changes in functional vision in patients with resolved endophthalmitis. This was a cross-sectional study. The study included 20 patients with resolved endophthalmitis and best-corrected visual acuity of 20/100 or better. Visual acuity (VA), contrast threshold (CT), red/green (RG) and yellow/blue (YB) colour vision and 15 Hz flicker modulation threshold (FMT) were assessed using standard psychophysical techniques. The median age was 54 years. The median visual acuity was 0.27 (~ 20/40—Snellen Equivalent) ((interquartile range [IQR]), 0.30) logMAR). The median log contrast threshold (CT) was − 1.13 (IQR, 0.36) log units (normative value for age-matched CT: − 1.61 log units). The median red/green (RG) and yellow/blue (YB) thresholds were 11.52 (IQR, 26.19) and 9.45 (IQR, 16.20) CAD units respectively, which were at least 5 times higher than age-matched normative RG and YB thresholds. The median central cone- mediated FMT was 17.64% (IQR, 23.40%), which was much higher compared to age-matched FMT (5.48% [IQR, 3.47]). Linear regression revealed significant relationship between contrast thresholds and foveal thickness (y = 0.001x−1.47, R2 = 0.20, p = 0.048). Though endophthalmitis may resolve with a good visual acuity, deficits in visual functions like chromatic discrimination, cone-mediated flicker and contrast sensitivity persist.

Highlights

  • To evaluate the changes in functional vision in patients with resolved endophthalmitis

  • Structural changes caused by endophthalmitis is typically captured by clinical examination and Optical Coherence Tomography (OCT), whereas the functional changes are captured only through only one visual function which is the best-corrected visual acuity and that remains the sole criterion for assessing the treatment outcomes

  • It has been shown that visual functions such as spatial contrast sensitivity, chromatic sensitivity and cone-mediated flicker sensitivity are useful in the management and evaluation of treatment outcomes in retinal ­diseases[4]

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Summary

Introduction

To evaluate the changes in functional vision in patients with resolved endophthalmitis. There is a need to test other parameters of visual functions such as contrast sensitivity (spatial and temporal) and chromatic sensitivity, which are processed in the different domains of visual processing Studying these visual functions would allow us a wider understanding of recovery of the various physiological mechanisms that mediate it and a finer comprehending of the profile of ocular complaints experienced by these patients, which can lead to better management. Each of these visual functions may act as additional useful outcome measures of treatment. We report the results of the various visual function parameters in eyes with resolved endophthalmitis

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