Visual evoked cortical magnetic fields to pattern reversal stimulation

Abstract

We studied visual evoked magnetic fields to pattern reversal stimulation in six healthy subjects. Similar to the N75-P100-N145 components in visual evoked potentials, triphasic deflections, N75m-P100m-N145m, were clearly observed around the midoccipital position. A very small component, P50m, was occasionally observed preceding the N75m. Equivalent current dipoles (ECDs) of the main deflection, P100m, to quadrant-field stimulation were estimated near or around the calcarine fissure contralateral to the stimulation. The vertical ECD location of the P100m to the upper quadrant-field stimulation was estimated significantly lower (0.81±0.45 cm) than those to lower stimulation. These results were compatible with the retinotopic organization of the visual cortex (cruciform model) and suggested that the P100m originated in the striate cortex. The small P50m, although only a small number of ECDs could be estimated reliably, was located in the contralateral visual cortex. ECDs of the N75m were estimated mainly near or around the contralateral calcarine fissure. ECDs of the N145m were estimated also retinotopically, but with a greater vertical distance (2.90±1.09 cm) between upper and lower quadrant-field stimulation. MR-overlaid ECDs of the N145m suggested that these originated in the extrastriate cortex. No ECD was estimated when a probe was placed at the midfrontal position.