Abstract
To analyze long-term visual development in children with Down syndrome who received early ophthalmological intervention. A total of 125 children with Down syndrome who were examined before 6years of age and followed up for more than 5years were selected. Visual development, refraction, visual acuity testing, and the prescription of spectacles were examined retrospectively. Mean visual acuity by age was as follows: 2years, 1.13±0.23 logarithm of the minimum angle of resolution (logMAR); 5years, 0.55±0.25 logMAR; 8years, 0.27±0.19 logMAR; 11years, 0.17±0.16 logMAR; and 14years, 0.10±0.15 logMAR. In 32 children (25.6%), visual acuity reached 0.0 logMAR or better. Hyperopia of +2D or more was observed in 132 eyes (52.8%), and astigmatism of 2D or more was observed in 153 eyes (61.2%). Subjective testing was difficult in many children prior to 4.5years of age, and grating acuity testing was necessary. Spectacles were prescribed at a mean age of 3.5±1.6years in 120 children (96.0%). The average duration until the spectacles were worn constantly was 9.0±9.3months. Early ophthalmological intervention and longitudinal care is important for children with Down syndrome.
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