Visual activity and its association with myopia stabilisation

Abstract

To evaluate the association between outdoor and nearwork activities at baseline and myopia stabilisation by age 15 in the Correction of Myopia Evaluation Trial (COMET). Correction of Myopia Evaluation Trial enrolled 469 children (ages: 6-11years) with spherical equivalent myopia between -1.25 and -4.50D, who were randomised to progressive addition or single vision lenses and followed for 5years in their original lenses. At baseline, families recorded the child's outdoor and nearwork activities for 3days within a week. Weekly hours spent in nearwork and outdoor activities were calculated for each participant. Refractions collected over 11years were fit using the Gompertz function to determine each participant's myopia stabilisation age. Myopia for each child was then categorized as stable/not stable by age 15. Half (233/469) of participants had usable baseline activity diaries and refraction data that could be fit with the Gompertz function, 59.7% (139/233) had stable myopia by age 15 and 40.3% had myopia that was not yet stable. The frequency of stable myopia was similar for the two categories (median split) of outdoor activities: 60% (71/118) for ≤9.0hours/week(-1) and 59% (68/115) for >9.0hours/week(-1) . 56% (64/114) of children reporting >21.0h of baseline weekly nearwork activity had stable myopia by age 15 compared to 63% (75/119) with ≤21.0h of near work (adjusted OR=0.74; 95% CI: 0.43-1.29). Using baseline nearwork as a continuous variable, the multivariable odds ratio for the association between baseline nearwork hours and stabilisation by age 15 is 0.98: 95% CI: 0.96-1.00, a result trending towards significance. While time spent in outdoor activities in childhood does not appear to be related to myopia stabilisation by age 15, less near work activity might potentially be associated with myopia stabilisation by that age.