Abstract
Aminohydroxylation of alkene is an important method for synthesizing 1,2‐amino alcohols, which are found in natural products, pharmaceutically active compounds and several marketed drugs. Herein, we report the development of visible‐light mediated copper‐catalyzed aminohydroxylation and aminoalkoxylation of alkenes. In contrast to expensive iridium, ruthenium, or organic‐dyes based photocatalysts, this protocol takes advantage of economical copper phenanthroline complex as a photocatalyst for the generation of N‐centred radical from N‐amino pyridinium salt. Furthermore, this protocol features a mild reaction conditions, broad substrate scope, and regiospecific.
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