Visibility graph analysis of temporal irreversibility in sleep electroencephalograms.

Abstract

The study of sleep has continued to garner increased attention. However, most studies assume stationarity of sleep electroencephalogram (EEG) signals, whereas they are typically nonlinear and nonstationary. Little work has focused on the time irreversibility of sleep EEG signals. Hence, the aim of this work is to reveal the temporally irreversible structures of rapid-eye-movement (REM) and non-REM sleep using a visibility algorithm, which is robust to nonstationarity and finite-size effect. Results show that the temporal structure of non-REM sleep is more irreversible than that of REM sleep. The degree of irreversibility is highest in slow-wave sleep. Moreover, statistical analysis suggests that aging is the major factor that affects the irreversibility of sleep signals, while gender and body mass index contribute insignificantly. The dominant role of slow oscillations on the irreversible structures of the sleep signals is also indicated.