Viscoelasticity: Fractal parameters studied on mammalian erythrocytes under shear stress

Abstract

In this work, experimental determinations are carried out using a home-made device called an erythrodeformeter, which has been developed and constructed for rheological measurements on red blood cells subjected to definite fluid shear stress. A numerical method formulated on the basis of the fractal approximation for ordinary and fractionary Brownian motion1 is proposed to evaluate the viscoelastic behavior of mammalian erythrocyte membranes. The diffraction pattern, which is circular when the mammalian erythrocyte membranes are at rest, becomes elliptical when the cells undergo shear stress. Photometric readings of light intensity variation along the major axis of the elliptical diffraction pattern are recorded during the creep and recovery process. These data series are used to calculate, fractal rheological parameters of self-affine Brownian motion on the erythrocytes, averaged over several millions of cells. Three different parameters over the time dependent process could be obtained, which are: correlation coefficient , correlation integral, andK2-entropy, and very different results were obtained.