Abstract

Visceral leishmaniasis complicating idiopathic CD4+ T-cell lymphocytopenia: 2 case reports.

Highlights

  • HIV infection leads to worse treatment outcomes in visceral leishmaniasis (VL) and increases the risk of post-treatment relapse, suggesting that similar effects may be observed in other low CD4+ T cell states [1]

  • VL infection in individuals with Idiopathic CD4+ T cell lymphocytopenia (ICL) is a little-reported clinical entity [4, 5, 6] and here we report in detail our experiences of 2 such patients from the Hospital for Tropical Diseases (HTD)

  • One patient has had complex refractory disease managed over the last 12 years, developing both ocular and dermal leishmaniasis and demonstrating how CD4 deficiency without HIV infection affects the clinical course of VL

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Summary

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Citation: Fox-Lewis A, Lockwood DNJ (2017) Visceral leishmaniasis complicating idiopathic CD4+ T-cell lymphocytopenia: 2 case reports. PLoS Negl Trop Dis 11(5): e0005412. https://doi.org/ 10.1371/journal.pntd.0005412 Funding: The authors received no specific funding for this work. Competing interests: The authors have declared that no competing interests exist.

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