Virulence Potential, Antimicrobial Susceptibility and Phylogenetic Analysis of Corynebacterium pseudotuberculosis Isolated from Caseous Lymphadenitis in Sheep and Goats in Duhok City, Iraq

Rezheen F. Abdulrahman

doi:10.17582/journal.aavs/2021/9.6.919.925

Abstract

Virulence Potential, Antimicrobial Susceptibility and Phylogenetic Analysis of Corynebacterium pseudotuberculosis Isolated from Caseous Lymphadenitis in Sheep and Goats in Duhok City, Iraq

Highlights

C. pseudotuberculosis is a Gram-positive, pleomorphic, non-motile, non-capsulated, non-spore forming, facultative intracellular microorganism causing caseous lymphadenitis (CLA) in sheep and goats (Baird and Fontaine, 2007; Guimarães et al, 2011; Umer et al, 2017; Parin et al, 2018; Guerrero et al, 2018)
Pseudotuberculosis From1090 of inspected carcasses of sheep and goats slaughtered at Duhok abattoir, 22 were infected with CLA (Abdulrahman et al, 2020; Issa et al, 2021)
This study reported for the first time the investigation of virulence genes, antibiotic susceptibility and phylogenetic analysis of 22 C. pseudotuberculosis isolates from slaughtered sheep and goats suffering from CLA for better understanding the epidemiology of C. pseudotuberculosis in Duhok ciry, Iraq

Summary

Introduction

C. pseudotuberculosis is a Gram-positive, pleomorphic, non-motile, non-capsulated, non-spore forming, facultative intracellular microorganism causing caseous lymphadenitis (CLA) in sheep and goats (Baird and Fontaine, 2007; Guimarães et al, 2011; Umer et al, 2017; Parin et al, 2018; Guerrero et al, 2018). C. pseudotuberculosis is classified into two biovars according to nitrate reduction activity including biovar ovis and biovar equi (Connor et al, 2000; Connor et al, 2007; Oliveira et al, 2016; Guerrero et al, 2018). The biovar ovis is a cause of CLA in sheep and goats, while biovar equi causes disease in horses, cattle and buffalo (Dorella et al, 2006; Ruiz et al, 2011; Oliveira et al, 2016). Virulence genes related to the pathogenicity of C. pseudotuberculosis have been identified using whole genome analysis allowing understanding pathogenicity of this bacterium (Ruiz et al, 2011). Ruiz et al (2011) reported the

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Discussion

Conclusion