Abstract
Streptococcus agalactiae, or group B streptococcus (GBS), is an important pathogen for pregnant women and neonates, which can cause preterm birth, stillbirth, maternal sepsis and neonatal invasive disease. GBS are highly heterogeneous in their virulence factor expression and thus can exist as commensal bacteria or become highly invasive. In the U.S., universal screening for GBS is performed at 37-38 weeks gestation and women testing positive are treated with intrapartum antibiotic prophylaxis to prevent neonatal invasive disease.
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