Virtual Source Synthetic Aperture for Accurate Lateral Displacement Estimation in Ultrasound Elastography.

Abstract

Ultrasound elastography (USE) is an emerging noninvasive imaging technique in which pathological alterations can be visualized by revealing the mechanical properties of the tissue. Estimating tissue displacement in all directions is required to accurately estimate the mechanical properties. Despite capabilities of elastography techniques in estimating displacement in both axial and lateral directions, estimation of axial displacement is more accurate than lateral direction due to higher sampling frequency, higher resolution, and having a carrier signal propagating in the axial direction. Among different ultrasound imaging techniques, synthetic aperture (SA) has better lateral resolution than others, but it is not commonly used for USE due to its limitation in imaging depth of field. Virtual source synthetic aperture (VSSA) imaging is a technique to implement SA beamforming on the focused transmitted data to overcome the limitation of SA in depth of field while maintaining the same lateral resolution as SA. Besides lateral resolution, VSSA has the capability of increasing sampling frequency in the lateral direction without interpolation. In this article, we utilize VSSA to perform beamforming to enable higher resolution and sampling frequency in the lateral direction. The beamformed data are then processed using our recently published elastography technique, OVERWIND. Simulation and experimental results show substantial improvement in the estimation of lateral displacements.