Abstract

A virilizing ovarian tumor in a 2 1/2-year-old girl, the youngest known patient, is described. Serum testosterone level was elevated; 24 hour excretion of urinary 17-ketosteroids was increased and was not suppressed by administration of dexamethasone. The histological appearance of the tumor was felt to be compatible with the diagnosis of lipoid cell tumor; virilization decreased after surgical removal. However, the patient died 17 months after initial diagnosis, from diffuse metastatic disease originating in an apparently unrelated undifferentiated sarcoma of the oropharynx.

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