Virilising Adrenocortical Oncocytomain a 16 Year Old Girl: A Rare Neoplasm

Abstract

Functioning adrenocortical oncocytomas are extremely rare and most reported patients are 40–60 years of age. Functioning adrenocoritcal oncocytomas are rare in children. We report a case of functioning adrenocortical oncocytoma in a 16-year-old female girl presenting with primary amenorrhea and virilisation. She presented with deepening of the voice and excessive hair growth, and elevation of plasma testosterone and dehydroepiandrosteronesulphate with normal catecholamines. We are describing the biochemical, radiological, operative and post-operative findings of this case. The tumour, which was well-encapsulated and circumscribed with 17 × 8 × 5 cm in size, was completely separated from kidney. The gross and microscopic study confirmed a case of adrenocortical oncocytic neoplasm of uncertain malignant potential. This tumour mass was removed successfully and patient was asymptomatic in routine follow-up.