Abstract
Suppression of viral multiplication by crude materials derived from a variety of sonically disrupted bacteria has been described (1,2). The inhibitory material from each bacterial species tested suppressed certain viruses without affecting the multiplication of others. Thus, while arboviruses are inhibited by material derived from an unclassified Coryne-bacterium, ECHO 11 is suppressed by material from Corynebacterium diphtheriae (both non-toxigenic and intermedius strains) and vaccinia is suppressed by material derived from various Escherichia coli serotypes and Salmonella typhimurium. The present report is concerned with further characterization of the material from E. coli 0111, using the multiplication of vaccinia virus in primary human amnion cell cultures as an indicator system. Preliminary observations concerning viral inhibition by nucleic acid derivatives are also included in this report.Preparation. An inoculum of E. coli 0111, obtained from Dr. J. G. Michael, was grown in one liter of Bacto nut...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
