Viral infection model with diffusion and state-dependent delay: Stability of classical solutions

Abstract

A class of reaction-diffusion virus dynamics models with intracellular state-dependent delay and a general non-linear infection rate functional response is investigated. We are interested in classical solutions with Lipschitz in-time initial functions which are adequate to the discontinuous change of parameters due to, for example, drug administration. The Lyapunov functions technique is used to analyse stability of interior infection equilibria which describe the cases of a chronic disease.