Abstract

本综述论文针对艾滋病病毒HIV转录研究的最新进展,对各种P-TEFb复合体的结构、功能、及其与艾滋病病毒HIV编码的Tat蛋白的相互作用、Tat的翻译后修饰、以及艾滋病病毒HIV的转录调控机制进行了综述,提高了对艾滋病病毒转录延伸机制的理解,创新性地提出了对抗艾滋病病毒感染及潜伏的新策略,在理论研究及应用方面意义重大。

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