Abstract
Viral hepatitis is one of the emerging public health problems, which urgently needs special attention. The disease has a varied presentation at the time of diagnosis, and it can progress from an accidental finding to life-threatening conditions like liver cirrhosis. It belongs to the rare group of diseases that can cause chronic inflammation inside the body, and it can have a delayed presentation. It contributes substantially to the global burden on healthcare. In terms of mortality, the burden due to viral hepatitis is similar to that of HIV and tuberculosis. It is among the major global public health challenges along with other communicable diseases, such as HIV, malaria, and tuberculosis; the major difference is that there are very limited preventive models in place for viral hepatitis, especially in developing countries like India. With limited resources for diagnosis and treatment, varied levels of presentation, and a rapidly increasing burden, it can become the next silent pandemic. In the current review, the authors aimed to compile the available global strategies for combating hepatitis, protocols available for disease surveillance, and the salient points from the national program for hepatitis control in India [National Viral Hepatitis Control Program (NVHCP)], and propose some recommendations. Ensuring a health facility equipped with a rapid diagnostic kit for screening, proper lab for the confirmation, robust Health Management Information System (HMIS) portal for the data management, and organizing regular workshops for physicians and lab technicians are some of the recommendations that we put forward.
Highlights
BackgroundGlobal burden: viral hepatitis as a public health concernViral hepatitis refers to a pathologic condition wherein an infection due to hepatitis viruses causes inflammation of the liver [1]
It is among the major global public health challenges besides other communicable diseases, such as HIV, malaria, and tuberculosis [3]
Among all deaths attributed to viral hepatitis, 96% were due to hepatitis B virus (HBV) (48%) and HCV (47%) alone [5]
Summary
Viral hepatitis refers to a pathologic condition wherein an infection due to hepatitis viruses causes inflammation of the liver [1]. It contributes substantially to the global burden on healthcare, with 248 million people infected with hepatitis B and 71 million infected with hepatitis C worldwide [2]. It is among the major global public health challenges besides other communicable diseases, such as HIV, malaria, and tuberculosis [3]. According to the World Health Organization Progress report on HIV, viral hepatitis, and sexually transmitted infections, the condition was responsible for 1.4 million deaths in the year 2016 [4]. According to the National Health Profile 2019 report, a total of 1,64,826 cases of viral hepatitis were detected in India in the year 2017, out of which 89,780 were men and 74,509 women, with a total of 537 deaths. 20-30% of all cirrhosis cases are due to chronic HBV infection while 12-20% are due to chronic HCV infection [10]
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