Abstract
Viral Etiology of Common Cold in Children, Finland
Highlights
Stored samples were subjected to nucleic acid testing (NAT) for picornaviruses; RSV; coronaviruses 229E, OC43, NL63, and HKU1; influenza C virus; human bocavirus (HBoV); human metapneumovirus (hMPV); and adenovirus
Other viruses were found in varying proportions: HBoV was present in 27 (14%) children; adenovirus was found in 23 (12%) (3 were positive by antigen detection, and 23 by NAT); enterovirus was present in 20 (10%); coronaviruses were found in 11 (6%) (NL63:7; HKU1:2; 229E/ OC43:2); influenza viruses were present in 11 (6%) (A:4; B:1; C:6); RSV was shown in 8 (4%); parainfluenza viruses were present in 7 (4%) (1:1; 3:6); and hMPV was found in 3 (2%)
Our study indicates that HBoV may be a common cause of common cold in young children
Summary
Viral Etiology of Common Cold in Children, Finland We examined the etiology of the common cold in young children who were newly symptomatic but had no need of hospital care. Stored samples were subjected to nucleic acid testing (NAT) for picornaviruses; RSV; coronaviruses 229E, OC43, NL63, and HKU1; influenza C virus; HBoV; hMPV; and adenovirus.
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