Abstract
Vilsmeier Haack (VH) acetylations of aromatic hydrocarbons have been carried out by using an N,N‐dimethyl acetamide (DMA)‐POCl3 system to afford the corresponding acetophenones in good yield with high regioselectivity. These acetylations are dramatically accelerated in micellar media. Further it is of interest to note that cyclizations in micellar media under VH conditions are obtained to afford 2‐chloro‐3‐acetyl quinoline derivatives in good yield. This procedure works efficiently in CTAB (cetyltrimethyl ammonium bromide), SDS (sodium dodecyl sulphate), and TX (Triton‐X100) media under reflux conditions (particularly for deactivated acetanilides).
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