Abstract
Visual field examination, visual evoked potentials (VEPs), and electroretinography (ERG) were assessed in 24 children (ages 3.5 to 18 years; mean age 13.3 years) who had received vigabatrin as monotherapy (5 children) or adjunctive therapy (19) for epilepsy for more than 6 months (3.0 +/- 1.6 years), in a retrospective study at the Shaare Zedek Medical Center, Jerusalem, Israel.
Highlights
Visual field examination, visual evoked potentials (VEPs), and electroretinography (ERG) were assessed in 24 children who had received vigabatrin as monotherapy (5 children) or adjunctive therapy (19) for epilepsy for more than 6 months (3.0 +/- 1.6 years), in a retrospective study at the Shaare Zedek Medical Center, Jerusalem, Israel
Visual field constriction (VFC) was diagnosed in 11 (65%) of 17 patients who could be examined by perimetry
Visual impairment in children with epilepsy treated with vigabatrin
Summary
Visual evoked potentials (VEPs), and electroretinography (ERG) were assessed in 24 children (ages 3.5 to 18 years; mean age 13.3 years) who had received vigabatrin as monotherapy (5 children) or adjunctive therapy (19) for epilepsy for more than 6 months (3.0 +/- 1.6 years), in a retrospective study at the Shaare Zedek Medical Center, Jerusalem, Israel. Seizure types were complex partial in 15, generalized tonic-clonic in 5, mixed in 4; and 3 had infantile spasms as babies. Visual field constriction (VFC) was diagnosed in 11 (65%) of 17 patients who could be examined by perimetry.
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