Abstract
Purpose: Video capsule Endoscopy (VCE) is one of the most complex procedures in digestive endoscopy. Delayed gastric emptying in diabetic patients has been cited as a possible reason for incomplete small bowel examination during a VCE. Since this relationship is not yet clearly established we decided to investigate it further. Methods: Case records of 412 consecutive (May 03 - Mar 07) VCE performed at a community based hospital were reviewed retrospectively. 51(12.4%) patients did not meet the inclusion criteria and were excluded. The Gastric transit time (GTT) and the Small Bowel Transit Time (SBTT) of diabetic patients (n=90, 24.9%) were compared with non-diabetic using a SPSS students version 16 (Spss Inc, Chicago). Results are expressed as mean ± SD. T-test was used for statistical analysis, p≤0.05 being significant. Results: 361 adult patients (male = 159, Age = 65 ± 16.2 years) were included in the study. The caecum was visualised in 83/91 (91%) diabetics and 241/270 (89%) in non-diabetics (p=0.59). In our experience there was no significant difference in the GTT (33.4, 1- 240 min vs. 35.52, 1- 264 min, p=0.67) and the SBTT (229.53, 38- 455 min vs. 245.15, 37-424 min, p= 0.12) between the diabetic and the non-diabetic groups respectively. Conclusion: The diagnostic yield of capsule endoscopy is affected by several factors which are not yet completely understood. GTT and SBTT are not affected statistically in patients with diabetes when compared with nondiabetics. This study highlights the need to perform prospective multi-institutional randomized control trials to further explore this relationship.
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