Abstract

s / Resuscitation 96S (2015) 5–42 35 nostrils at different flow rates. Pigs possess a carotid rete which is surrounded by the cavernous sinus; together these serve as an effective heat exchanger for the brain. However, in mammals in which the carotid rete ismissing such as rabbits and humans, some suggest that there is no effective heat exchange in the cavernous sinus and, consequently, SBC is not efficient in these species. In this study, we evaluate the effectiveness of this approach on rabbits and compare it with previous finding on newborn piglets. Materials and methods: Experiments were conducted on six rabbits. Body temperature was measured continuously using an oesophageal and a rectal temperature probe while brain temperature was measured with an implanted thermometer. Two successive experimentswere performedon each animal. In the first experiment, brain cooling was initiated by blowing room temperature air at a flow rate of 14–15L/min into both nostrils for 60min. The brain was then allowed to gradually rewarm to the baseline temperature. Following rewarming, the second series of measurements and brain cooling was performed in the samemanner as the first one but blowing cold air (−7 ◦C) at the same flow rate. Results: One hour post cooling with room temperature air at a flow rate of 14-15 L/min, the brain temperature was 34.1±1.2 ◦C which resulted inmean brain cooling rates of 3.7±0.9 ◦C/h. (Fig. 1a) Brain temperature could be reduced more rapidly at mean rates of 5.2±1.9 ◦C/h,while thebody temperaturewasmaintainedabove 36 ◦C. (Fig. 1-b) Mean brain cooling rate was significantly greater with−7 ◦C as comparedwith room temperature air in both species.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.