Abstract
Viburnum opulus (VO) is a valuable decorative, medicinal, and food plant. This deciduous shrub is found in natural habitats in Europe, Russia, and some regions in North Africa and North Asia. The VO is traditionally used to treat aliments such as cough, colds, tuberculosis, rheumatic aches, ulcers, stomach, and kidney problems, among others. Many of the health-promoting properties of VO are associated with antioxidant activity, which has been demonstrated in both in vitro and in vivo studies. The results of in vitro studies show the antimicrobial potential of VO, especially against Gram-positive bacteria. In cell-based studies, VO demonstrated anti-inflammatory, anti-obesity, anti-diabetic, osteogenic, cardio-protective, and cytoprotective properties. The applicability of VO in the treatment of urinary tract diseases, endometriosis, and some cancers has been confirmed in in vivo studies. The health benefits of VO result from the presence of bioactive components such as phenolic compounds, vitamin C, carotenoids, iridoids, and essential oils. The aim of this review is to present an overview of the botanical characteristics, chemical compositions, including bioactive compounds, and pro-health properties of VO different morphological parts.
Highlights
Viburnum opulus (VO) is a plant that belongs to the Viburnum L. genus from Adoxaceae family, sometimes included in the monotypic family Viburnaceae, formerly for the Caprifoliaceae
The results showed that VO proanthocyanidins applied orally in doses of 25, 50, or 75 mg/kg body weight increased the activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in gastric mucosa, inhibited the production of reactive oxygen species (ROS), and decreased the expression by tissue concentration of malondialdehyde comes from lipid peroxidation
Malondialdehyde level in the lung tissue, which corresponds to lipid peroxidation of cellular membranes, as well as level of plasma protein carbonyl, were reduced in rats treated with VO fruit extract
Summary
Viburnum opulus (VO) is a plant that belongs to the Viburnum L. genus from Adoxaceae family, sometimes included in the monotypic family Viburnaceae, formerly for the Caprifoliaceae. The results of the studies by Çemtekin et al [14] suggested the possibility of using VO fruit concentrate in cooked minced turkey as an alternative antioxidant source for nitrites and butylated hydroxytoluene to delay oxidative changes. The gilaburu juiceulcers, is traditionally used todiabetes, treat and hypertension as well as to prevent some stomach and kidney problems [6,11,13,15,16] The ailments such as cough, colds, tuberculosis, rheumatic aches, ulcers, liver disease, diabetes, bark and of VOhypertension (Cortex Viburni) is used in the treatment of stomach or uterine bleeding and hemorrhoids [17].
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