Abstract
Some of the important features of the bands occur in the present study. The band called amide A is available in all the diseased and healthy controls and the frequency of the band ranges from 3380 cm﹣1 to 3480.74 cm﹣1. The band due to C-H band and called hydrocarbon band was found only in paralytic and Alzheimer diseased along with normal healthy controls. Carbide band (C=C) is found only in Duchenne muscular dystrophy, paralytic and Alzheimer’s disease patients. Amide I was intact in all disorders with normal persons. Peroxide band (O-O) was found in all the cases of study. Amide IV band was found in paralytic, muscular dystrophy, Alzheimer’s diseases and normal controls. The amide V band was found in Alzheimer’s diseases only. The appearance or disappearance of the bands is a good sign to understand the mechanisms at the molecular level. FTIR spectroscopy may help in the diagnosis of the disease at the early stage of the onset. This spectroscopy can be used nicely for the study of hair, vaginal fluid, nails, urine, mucus, semen, synovial fluid, blood, hemoproteins, skin, and tears for human beings. We can also use it to understand the effect of adulteration on food and paint technology. FTIR is an indicator to explore the changes occurring at molecular level.
Highlights
Our main attention is concentrated on Fourier Transform Infrared (FTIR) Spectroscopy
Blood samples of the epileptic children, migraineous, paralytic, Alzheimer’s disease and muscular dystrophy patients along with normal healthy controls were collected from the Department of Neurology, I.H.B.A.S., New Delhi after the approval of ethical committee of the hospital. 10 ml. of freshly drawn blood was collected in siliconised screw capped test tubes
Amide IV band is found in some cases of Duchenne Muscular Dystrophy (DMD), Alzheimer’s disease and normal samples only
Summary
Our main attention is concentrated on Fourier Transform Infrared (FTIR) Spectroscopy. How to cite this paper: Kumar, S., et al (2014) Vibrational Studies of Different Human Body Disorders Using FTIR Spectroscopy. FTIR is based on the fundamental principle of molecular spectroscopy. This broad ranging area of physics and chemistry covers multitude experimental techniques. We would like to give some facts regarding the principle of this technique. Specific molecules absorb light energy at specific wavelengths. Water molecule (H2O) resonates around 3450 cm−1 (wave number in unit) in the infrared region of the electromagnetic spectrum
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