Veterinary antibiotics in swine and cattle wastewaters of China and the United States: Features and differences.

Abstract

Veterinary antibiotics (VAs) have been widely used in livestock for disease prevention, treatment, and growth promotion. This study compared top 20 VAs in Chinese and US swine and cattle wastewater with published literatures. The sulfonamides (SAs) were found to be predominant, accounting for 62% of the top 20 VAs in Chinese swine wastewater, while tetracyclines (TCs) contributed to about 68.7% of the 18 VAs in US swine wastewater. The average concentration of the 20 major VAs in Chinese swine wastewater was estimated to be 1145μg/L against 253.6μg/L in the United States. On the other hand, the five major VAs in Chinese cattle wastewater were identified to be oxytetracycline, nafcillin, apramycin, lincomycin, and amikacin, while monensin was found to be dominant in US cattle wastewater. The average concentration of the top 20 VAs in Chinese and US cattle wastewaters were found to be 54.6 and 46.2μg/L, respectively. These analyses suggested that VAs were probably over-used in Chinese swine industry, eventually causing the development and spreading of antibiotic resistant-bacteria and genes, which should be paid with attention. PRACTITIONER POINTS: Major veterinary antibiotics (VAs) in swine and cattle wastewater were identified. Top 20 VAs in swine and cattle wastewater of China and the United States were compared. VAs concentration in Chinese swine wastewater was 4.52 times that in the United States. VAs concentration in Chinese cattle wastewater was 1.18 times that of the United States.