Abstract

Sympathetic activation is important for postural blood pressure regulation. Historically, the baroreflexes have been considered the primary mechanism responsible in regulating blood pressure during standing in humans. Data from natural head movement studies indicate that the vestibular system contributes to muscle sympathetic activation and contributes to postural blood pressure changes in humans. The otolith organs and not the semicircular canals are responsible for increases in muscle sympathetic nerve activity. A number of factors can modify the vestibulosympathetic reflex including aging, bed rest, exercise training, and hydration status. All these factors, which attenuate the vestibulosympathetic reflex, are associated also with decrease orthostatic tolerance. This presentation will examine the relation between the vestibulosympathetic reflex and postural blood pressure control in humans.

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