Abstract
Our clinical and experimental observations allowed us to identify a few pathogenetic mechanisms of vestibular dysfunctions formed in chronic brain ischemia. In an experimental part of the study carried out on rats, we estimated the pathogenetic significance of vascular disorders within the vestibularbasilar basin resulting in modifications of motor and postural behavior, coordination of muscular activity, and psycho-emotional disorders; these changes demonstrated no positive dynamics in the course of the experiment. In the clinical part, vestibular dysfunctions observed against the background of osteochondrosis of the vertebral column were combined with autonomic dysfunctions and disorders of autonomic supply of the organism’s functions. Original pathonegetically oriented therapy of vestibular dysfunctions under conditions of chronic cerebral ischemia against the background of vertebral osteochondrosis allows physicians to significantly improve the general state of the patient, state of cerebral hemodynamics, autonomic status, postural control, control of locomotion, and also to smooth the accompanying psychoemotional effects.
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