Abstract

Very high levels of SGOT (1710, 2450 and >1250) and LDH (1275, 1740 and 1300) are reported in 3 cases of extrahepatic obstruction due to gallstones. The diagnoses were established at operation, and viral hepatitis was ruled out by liver biopsy. Marked SGOT elevations in extrahepatic biliary obstruction are rare, but isolated case reports and experimental biliary obstruction in animals support the observation that SGOT values in excess of 1000 units can occur as a result of the obstructive process.

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