Abstract

Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue.

Highlights

  • Babesiosis is usually acquired from a tick bite or through a blood transfusion

  • This case provided convincing evidence for congenital babesiosis because of prepartum infection involving the placenta in the mother

  • On the basis of experience with congenital malaria, we assume that Babesia spp. parasites cross the placenta during pregnancy or at the time of delivery [11,12]

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Summary

Introduction

Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. Routine examination of a peripheral blood smear showed B. microti in 4% of erythrocytes (Figure); a blood sample from the infant was positive by PCR for B. microti DNA. The heel-stick blood sample obtained on the infant’s third day of life as part of newborn screening was tested and found to be negative for B. microti by PCR [5] and for IgM but total antibody positive (>128) (online Technical Appendix).

Results
Conclusion

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