Abstract
Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue.
Highlights
Babesiosis is usually acquired from a tick bite or through a blood transfusion
This case provided convincing evidence for congenital babesiosis because of prepartum infection involving the placenta in the mother
On the basis of experience with congenital malaria, we assume that Babesia spp. parasites cross the placenta during pregnancy or at the time of delivery [11,12]
Summary
Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. Routine examination of a peripheral blood smear showed B. microti in 4% of erythrocytes (Figure); a blood sample from the infant was positive by PCR for B. microti DNA. The heel-stick blood sample obtained on the infant’s third day of life as part of newborn screening was tested and found to be negative for B. microti by PCR [5] and for IgM but total antibody positive (>128) (online Technical Appendix).
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