Abstract
To determine whether it is possible to vertically augment bone utilizing a block graft from compressed titanium granules mainly used previously for contained bone defects and to determine whether there exists a difference in osteoconductive properties between the white and the grey granules. In 11 rabbits, 4 titanium blocks were inserted on each rabbit's skull bone according to a randomized scheme. These blocks were made from standardized compressed titanium granules. Type A: PTG grey, small granules (Pourus Titanium Granules, Tigran, Malmö, Sweden); Type B: PTG grey, large granules; Type C: PTG white, small granules; Type D: PTG white large granules. After 12 weeks, the animals were sacrificed and specimens were collected for histology and μCT scanning. From both the μCT and histology, it can be said that bone formation was successfully achieved for all groups, and the granules maintained their volume. The histomorphometric BA (bone area) evaluation in the entire grafted area presented that there were no statistical differences between all groups tested. The lowest 1/4 BA in contact with the rabbit skull presented that groups A and C presented the highest mean BA, and group A presented significantly higher BA than that of group D (p = 0,049). No significant differences were noted between groups A, B and C. Within the limitation of this study, no differences were noted between small white or grey PTG blocks. The large granules presented less bone ingrowth area compared to the small granules and this trend was regardless of the different PTG types. The entire grafted area was not filled with new bone suggesting that bone migration occurred mostly from the existing cortical bone side suggesting contact osteogenesis.
Highlights
After tooth extraction, the alveolar bone undergoes remodeling, which results in vertical and horizontal bone resorption (Araujo & Lindhe, 2005)
The study presented that there were no differences in osseointegration properties, regarding histomrorphometic bone to implantat contact 37% for white porous titanium granules (WPTG), 67% for porous titanium granules (PTGs), and 61% for the sham group, for implants placed after bone reconstruction (Verket et al, 2014), which is an indication that the modified material may be used with comparable prognosis before implant treatment as the original titanium granule
All PTG blocks were stable at time of grafting, and there were no signs of infection
Summary
The alveolar bone undergoes remodeling, which results in vertical and horizontal bone resorption (Araujo & Lindhe, 2005). The autogenous bone is known for its rapid resorption during the healing phase, and some reports indicate that approximately 40% of the graft will resorb during the early phase (Abrahamsson, Walivaara, Isaksson, & Andersson, 2012; Cordaro, Amade, & Cordaro, 2002) As a result, this could lead to the collapse of the augmented site, which may affect the subsequent implant placement. The study presented that there were no differences in osseointegration properties, regarding histomrorphometic bone to implantat contact 37% for WPTG, 67% for PTG, and 61% for the sham group, for implants placed after bone reconstruction (Verket et al, 2014), which is an indication that the modified material may be used with comparable prognosis before implant treatment as the original titanium granule. Clinicians might be tempted to conduct an overcorrection in order to obtain sufficient volume of the peri‐implant tissue
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
