Abstract

We describe a 29-year-old woman with chronic migraine and psychiatric comorbidities that presented with new transient left-sided hemiparesis and hemi-hypoesthesia and were found to have right vertebral artery hypoplasia (VAH). We briefly review the association of VAH and migraine and the influence of psychiatric disorders and VAH as possible risk factors for chronification of episodic migraine. Despite uncertain mechanisms, VAH may be one of thecontributing factors for the chronicity of migraine.

Highlights

  • Vertebral artery hypoplasia (VAH) is an uncommon variation of the posterior circulation

  • Little is known about its clinical relevance, and recently, VAH has been considered a risk factor for migraine with aura, vestibular migraine, and posterior circulation stroke.[2]

  • We describe a case of vertebral artery hypoplasia in a patient with chronic migraine associated with psychiatric disorders and briefly review the literature

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Summary

Introduction

Vertebral artery hypoplasia (VAH) is an uncommon variation of the posterior circulation. A 29-year-old woman with a previous history of migraine without aura was admitted to the emergency department (ED) of a tertiary neurological center with new sudden onset of left-sided hemiparesis and hemihypoesthesia, with a duration of one minute. After these symptoms, she developed a headache with migraine characteristics, identical to her previous episodes. The duration was between 12-24 hours and used to improve with analgesic (dipyrone 500 mg or dipyrone 300 mg + caffeine 50 mg + orphenadrine 35 mg) She has been taking these medications more than 15 days per month in the last two years. She was diagnosed with chronic migraine and prescribed topiramate with a progressive dose increasing up to 100 mg per day as a preventive treatment for migraine

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