Abstract
Cancer refers to a group of illnesses that result from cell population in the body increasing unusually. These cells break up and create new cells in an uninhibited mode that can extend in the body and cause injury to vital organs. Analytical chemistry is the division of chemistry involved in separating, identifying and determining the relative quantity of the components in a sample. Analytical method development and validation play vital role in method development and manufacture of pharmaceuticals. The objective of this review article is to study divergent types of anticancer drugs and the different analytical methods assessed during their determination, like UV-Visible Spectrophotometer, GC, Mass Spectrophotometer, NMR, LC-MS, GC-MS and FT-IR. The involvement for analytical methods to establish an anticancer drug is of utmost importance. The development and validation of analytical methods is mandatory for preclinical and clinical studies and even for the development of formulations containing these compounds. This constitutes the next challenge in the analysis of anticancer drugs. This review outlines the recent position of method development and validation of anticancer drugs in bulk and solid dosage forms.
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