Abstract
Immunocompromised cutaneous district (ICD) or locus minoris resistentiae is an old concept in dermatology, which represents vulnerability of a particular cutaneous site to the development of secondary dermatosis due to prior insults. Seborrheic keratosis (SK) is an asymptomatic benign epidermal keratinocytic tumor, commonly seen in elderly patients. It may also act as an acquired cutaneous lesion offering lesser resistance for the development of other dermatosis. A 65-year-old female patient having SK over cheek developed a new lesion of verruca vulgaris over it. So far as published literature is concerned, this is the first report of verruca vulgaris superimposed over SK; thus, the latter is acting as an example of immunocompromised cutaneous district (ICD).
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