Veridical stimulus localization is linked to human area V5/MT+ activity

Abstract

How the brain represents visual space is an unsolved mystery. Spatial localization becomes particularly challenging when visual information processing is briefly disrupted, as in the case of saccadic eye movements, blinks, or visual masks. As we have recently reported, a compression of visual space, illustrated by displacements of shortly flashed stimuli, can be observed in the temporal vicinity of masking stimuli during ocular fixation (Zimmermann et al., 2013). We here aimed at investigating the neural mechanisms underlying these displacements using functional magnetic resonance imaging. On the behavioral level, we detected significant stimulus displacement when visual masks were simultaneously presented. At the neural level, we observed decreased human motion complex V5/MT+ activation associated with these displacements: When comparing trials with a perceived stimulus shift in space to trials of veridical perception of stimulus localization, human V5/MT+ was significantly less activated although no differences in perceived motion can account for this. Data suggest an important role of human V5/MT+ in the process of spatial localization of briefly presented objects and thus extend current concepts of the functions of human V5/MT+.