Verdacht auf Mammakarzinom (BI-RADS™ 5) - Einsatz der sonographisch geführten Vakuumbiopsie (LCNB) nach histologisch primär negativer konventioneller Hochgeschwindigkeitsstanzbiopsie (CNB)

Abstract

Purpose: The aim of our study was to evaluate sonographically guided vacuum-assisted large core needle biopsy (LCNB) after primary histological negative core needle biopsy (CNB) after suspicion of breast cancer (BI-RADS 5). Material and Methods: From 07/2004 to 09/2004 we investigated 94 patients for suspicion of breast cancer (BI-RADS 5 or sonographically BI-RADS analog). The age of the patients was 28-81 years (median: 54 years), tumour size 3-55 mm (median: 19 mm). We performed a sonographically guided large core needle biopsy (Bard-Angiomed®) in all patients and if there was a difference between histology and complementary breast diagnosis we carried out in the following a sonographically guided vacuum-assisted large core needle biopsy (Vacora®, Bard-Angiomed®). Results: In 86 of the 94 lesions the malignancy was confirmed by the sonographically guided core needle biopsy (corresponding to 91 %) and subsequent operation. In 8 lesions (corresponding to 9%) we found a benign histology and we carried out a sonographically guided vacuum-assisted large core needle biopsy. The result in 4 patients was now malign with an operation required on the next day and at 4 cases benign. The 4 lesions with a benign histology demonstrated no progression in the follow-up at 3 months. Conclusion: Sonographically guided vacuum-assisted large core needle biopsy instrumentation (LCNB) is an excellent additional diagnostic tool. In lesions classified as BI-RADS 5 with negative histology after sonographically guided core needle biopsy (CNB) it offers a good histological assessment.