Abstract
AbstractThe treatment of infectious diseases has increasingly become a serious problem as the pathogens are rapidly acquiring resistance against the current antibiotics. The herb Verbena officinalis has a great repute as ethnomedicine against infections. Keeping in view its immense medicinal scope, the present study was designed. Antimicrobial potential of its stems, leaves, and roots was evaluated against 24 strains of Gram-positive and Gram-negative bacteria. Ethanolic extracts of stems, leaves, and roots of V. officinalis and their fractions in various solvents were assessed. The stems proved to be most potent against all the strains. Its activity against Staphylococcus aureus and Pseudomonas aeruginosa was higher than the antibiotic Amoxicillin. The leaves also showed considerable activity against P. aeruginosa, Citrobacter freundii, and S. aureus. The roots turned out to be highly effective against Bacillus subtilis, S. aureus, and P. aeruginosa. The study confirmed the efficacy of V. officinalis aga...
Highlights
Plants have been used worldwide for treatment of various human ailments since antiquity [1, 2]
Many medicinal plants have been screened for their antimicrobial activity and to treat different diseases caused by the pathogens [29,30,31,32,33,34]
In our previous study [7], we worked on comparison of antimicrobial potential of ethanolic extracts of various parts of V. officinalis against five reference stains and eight clinically isolated bacteria
Summary
Plants have been used worldwide for treatment of various human ailments since antiquity [1, 2] Their use is still quite prevalent, especially in developing countries in the form of traditional medicine [3]. Extensive chemical and pharmacological studies on medicinal plants during the last many decades have led to the validation of traditional claims in many cases and have facilitated identification of their pharmacologically active components. These active principles have provided leads in the development of several drugs [4]. The antimicrobial resistance is a serious hazard to public health and requires immediate efforts to discover more effective antibiotic agents
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