Abstract
Coordinated manner of action of the projections from monoaminergic cell groups, cholinergic and orexin neurons...
Highlights
Coordinated manner of action of the projections from monoaminergic cell groups, cholinergic and orexin neurons, produces arousal
There is an important role for the Ventrolateral Preoptic Nucleus (VLPO) to inhibit the arousal circuits during sleep
VLPO has two groups of neurons: One group located in the core of the VLPO and its neurons project to the tuberomammillary nucleus and the other group of neurons which is called extended VLPO, projects to the median and dorsal raphe nuclei and locus coeruleus, tuberomammillary nucleus and dorsal raphe as the arousal system components on one hand and VLPO on the other hand would be inhibitory in the mutual manner [4,5,6]
Summary
Coordinated manner of action of the projections from monoaminergic cell groups, cholinergic and orexin neurons, produces arousal. Ventrolateral Preoptic Nucleus (VLPO) Role in Turning the Ascending Arousal System Off During Sleep Behzad Saberi* Medical Research, Esfahan, Iran *Corresponding author: Behzad Saberi, Medical Research, Esfahan, Iran
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