Abstract
1. 1. The literature on the treatment of ventricular tachycardia with quinidine and with procaine amide is briefly reviewed. 2. 2. Three cases of serious cardiac depression occurring with procaine amide properly administered intravenously are reported. One of these patients died immediately after the injection. 3. 3. The possible mechanism of this reaction is discussed. 4. 4. Recommendations are made regarding the use of intravenous procaine amide. The drug should probably not be given by this route in septal infarction, bundle branch block, and auriculoventricular block.
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