Abstract
Current Radiation Therapy (RT) planning for lung stereotactic body radiation therapy (SBRT) is based on dose volume histogram such as V20 and mean lung dose to avoid radiation induced lung injury based on the assumption that the pulmonary function is the same everywhere inside lung. However, the actual lung function is indeed region specific and it can be incorporated into RT planning for functional lung avoidance. We have previously developed ventilation imaging methods coupling either free breathing 4DCT or breath hold MRI with deformable image registration.
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