Venous Thromboembolism Polygenic Risk Score Associates With Pulmonary Hypertension in the UK Biobank.

Abstract

HomeCirculation: Genomic and Precision MedicineVol. 15, No. 6Venous Thromboembolism Polygenic Risk Score Associates With Pulmonary Hypertension in the UK Biobank No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextVenous Thromboembolism Polygenic Risk Score Associates With Pulmonary Hypertension in the UK Biobank Katharine R. Clapham, MD, Md Mesbah Uddin, PhD, Michael C. Honigberg, MD, MPP, Thomas Gilliland, MD, Yunfeng Ruan, PhD and Pradeep Natarajan, MD, MMSc Katharine R. ClaphamKatharine R. Clapham https://orcid.org/0000-0003-3659-4755 Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital (K.R.C.). Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA (K.R.C., M.M.U., M.C.H., T.G., P.N.). Search for more papers by this author , Md Mesbah UddinMd Mesbah Uddin https://orcid.org/0000-0003-1846-0411 Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA (K.R.C., M.M.U., M.C.H., T.G., P.N.). Search for more papers by this author , Michael C. HonigbergMichael C. Honigberg https://orcid.org/0000-0001-8630-5021 Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Cardiology Division, Massachusetts General Hospital (M.C.H., T.G., P.N.). Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (M.C.H., T.G., P.N.). Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA (K.R.C., M.M.U., M.C.H., T.G., P.N.). Search for more papers by this author , Thomas GillilandThomas Gilliland https://orcid.org/0000-0002-2872-9608 Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Cardiology Division, Massachusetts General Hospital (M.C.H., T.G., P.N.). Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (M.C.H., T.G., P.N.). Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA (K.R.C., M.M.U., M.C.H., T.G., P.N.). Search for more papers by this author , Yunfeng RuanYunfeng Ruan https://orcid.org/0000-0002-3213-8309 Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Search for more papers by this author and Pradeep NatarajanPradeep Natarajan Correspondence to: Pradeep Natarajan, MD, MMSc, Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, 185 Cambridge St Boston, MA 02114. Email E-mail Address: [email protected] https://orcid.org/0000-0001-8402-7435 Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge (K.R.C., M.M.U., M.C.H., T.G., Y.R., P.N.). Cardiology Division, Massachusetts General Hospital (M.C.H., T.G., P.N.). Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (M.C.H., T.G., P.N.). Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA (K.R.C., M.M.U., M.C.H., T.G., P.N.). Search for more papers by this author Originally published9 Nov 2022https://doi.org/10.1161/CIRCGEN.122.003797Circulation: Genomic and Precision Medicine. 2022;15FootnotesFor Sources of Funding and Disclosures, see page 606 & 607.Correspondence to: Pradeep Natarajan, MD, MMSc, Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, 185 Cambridge St Boston, MA 02114. Email [email protected]harvard.edu