Venous and arterial thromboses in association with carcinoma of the pancreas.

Abstract

Case Reports1 July 1955VENOUS AND ARTERIAL THROMBOSES IN ASSOCIATION WITH CARCINOMA OF THE PANCREASDAVID BUTTROSS JR., M.D., JOHN SALATICH, M.D.DAVID BUTTROSS JR., M.D.Search for more papers by this author, JOHN SALATICH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-1-213 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTrousseau1 in 1865 appears to have been the first to mention an increased incidence of thrombophlebitis in patients with carcinoma. Only recently, however, has the rather striking incidence of venous thrombosis and pulmonary embolism associated with cancer of the pancreas been given much attention in the literature.2-18 In only one of these articles13 is mention made of arterial as well as venous thromboses in cases of pancreatic carcinoma. Although there has been considerable speculation,3, 4, 10 the cause of this increased susceptibility to thrombo-embolic phenomena has not been determined.We have observed numerous cases of carcinoma of the pancreas in...Bibliography1. Trousseau A, quoted by Thompson,2 Clinical Medicine del Hotel Dieu de Paris 3: 80, 1877. Google Scholar2. Thompson AP: Thrombosis of the peripheral veins in visceral cancer, Clin. J. 67: 137-140, 1938. Google Scholar3. Sproul EE: Carcinoma and venous thrombosis: the frequency of association of carcinoma in the body and tail of the pancreas with multiple venous thrombosis, Am. J. Cancer 34: 566-585, 1938. Google Scholar4. JenningsRussell WIWO: Phlebothrombosis associated with mucin-producing carcinomas of the tail and body of the pancreas, Arch. Surg. 56: 186-198, 1948. CrossrefMedlineGoogle Scholar5. Edwards EA: Migrating thrombophlebitis associated with carcinoma, New England J. Med. 240: 1031-1035, 1949. CrossrefMedlineGoogle Scholar6. Clinicopathological Report: Multiple pulmonary emboli in association with carcinoma of the pancreas, New England J. Med. 237: 875-878, 1947. MedlineGoogle Scholar7. MikalCampbell SAJ: Carcinoma of the pancreas, Surgery 28: 963-989, 1950. MedlineGoogle Scholar8. SmalleyEusterman REGB: Pancreatic carcinoma: report of two cases with unusual symptoms, Proc. Staff Meet., Mayo Clin. 18: 444-449, 1943. Google Scholar9. Kenney WE: Association of carcinoma in body and tail of pancreas with multiple venous thrombosis, Surgery 14: 600-609, 1943. Google Scholar10. PrattPratt TDJH: Early diagnosis of carcinoma of pancreas based on clinical and pathological study of 100 autopsy cases, Am. J. M. Sc. 222: 349-363, 1952. Google Scholar11. LevyLichtman HSS: Clinical characterization of primary carcinoma of body and tail of pancreas, Arch. Int. Med. 65: 607-626, 1940. CrossrefGoogle Scholar12. Duff GL: Clinical and pathological features of cancer of body and tail of pancreas, Bull. Johns Hopkins Hosp. 65: 69, 1939. Google Scholar13. ThompsonRogers CMLR: Analysis of the autopsy records of 157 cases of carcinoma of the pancreas with particular reference to the incidence of thromboembolism, Am. J. M. Sc. 223: 469-478, 1952. CrossrefMedlineGoogle Scholar14. CooperBarker TNW: Recurrent venous thrombosis, early complication of obscure visceral carcinoma, Minnesota Med. 27: 31-36, 1944. Google Scholar15. Ingelfinger FJ: Diagnosis of carcinoma of pancreas, New England J. Med. 235: 653-661, 1946. CrossrefMedlineGoogle Scholar16. Franco SC: Carcinoma of head of pancreas, review of 40 cases, Am. J. Digest. Dis. 8: 65-69, 1941. CrossrefGoogle Scholar17. Grauer FW: Pancreatic carcinoma: review of 34 autopsies, Arch. Int. Med. 63: 884-898, 1939. CrossrefGoogle Scholar18. QuijanoRojas ME: Epigastric pain and thrombophlebitis in patients with carcinoma, Rev. Invest. Clin. 3: 337-347, 1951. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication July 24, 1954.From the Department of Medicine, Louisiana State University School of Medicine, and Charity Hospital, New Orleans, Louisiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPankreasPREVALENCE OF THROMBI IN CARCINOMA OF THE PANCREASA morphologic study of pancreatic carcinoma with reference to multiple thrombi 1 July 1955Volume 43, Issue 1Page: 213-216KeywordsHospital medicinePancreasPancreatic cancerPulmonary embolismThrombosis ePublished: 1 December 2008 Issue Published: 1 July 1955 PDF downloadLoading ...